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Literature summary extracted from

  • Plumbridge, J.
    Control of the expression of the manXYZ operon in Escherichia coli: Mlc is a negative regulator of the mannose PTS (1998), Mol. Microbiol., 27, 369-380.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.191 additional information Escherichia coli the enzyme is the major transporter for D-mannose and also transports efficiently D-glucose, 2-deoxyglucose, D-fructose, N-acetylglucosamine, and glucosamine ?
-
 ?
2.7.1.191 [protein]-Npi-phospho-L-histidine + D-mannose[side 1] Escherichia coli
-
 [protein]-L-histidine + D-mannose 6-phosphate[side 2]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.191 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.191 additional information the enzyme is the major transporter for D-mannose and also transports efficiently D-glucose, 2-deoxyglucose, D-fructose, N-acetylglucosamine, and glucosamine Escherichia coli ?
-
 ?
2.7.1.191 [protein]-Npi-phospho-L-histidine + D-mannose[side 1]
-
 Escherichia coli [protein]-L-histidine + D-mannose 6-phosphate[side 2]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.191 enzyme II
-
 Escherichia coli
2.7.1.191 mannose PTS
-
 Escherichia coli
2.7.1.191 manXYZ the manXYZ operon (previously ptsM,ptsL) encodes three proteins forming the enzyme II of the so-called mannose PTS which is the major transporter for D-mannose and also transports efficiently D-glucose, 2-deoxyglucose, D-fructose, N-acetylglucosamine, and glucosamine Escherichia coli

Expression

EC Number Organism Comment Expression
2.7.1.191 Escherichia coli manX gene expression is negatively regulated by NagC and Mlc proteins down